The OROBOROS Oxygraph-2k
- to explore the Power of Life
for high-resolution respirometry (HRR)
O2k with simultaneous fluorometry: HRR and ROS production, mt-membrane potential, ATP-production, Ca2+
>> More details? Consult Bioblast
O2k high-output, low running costs.
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O2k - the world's most Powerful, Popular and Prestigeous respirometer for cellular and mitochondrial research:
• Isolated mitochondria, • Intact cells, • Permeabilized cells, • Permeabilized tissues, • Tissue homogenates, • Small tissue biopsies
Our Administration Office is closed for the Christmas period from Monday 23rd December 2013 up to and including Monday 6th January 2014. We will be here for you again from Tuesday 7th January 2014. We would like to take this opportunity to thank you for your custom and also to send you and your team “Season´s Greetings”.
O2k for OXPHOS analysis with substrate-uncoupler-inhibitor titration (SUIT) protocols to study multiple respiratory states in a single experimental incubation: no other platform is suited for application of SUIT protocols.
'OXPHOS analysis extends simple bioenergetics to the level of mitochondrial physiology' (Gnaiger 2012).
O2k - flexibility within experiments, on-line display of concentration and flux, automatic software controlled titrations.
Reference: Gnaiger E (2008) Polarographic oxygen sensors, the oxygraph and high-resolution respirometry to assess mitochondrial function. In: Mitochondrial Dysfunction in Drug-Induced Toxicity (Dykens JA, Will Y, eds) John Wiley: 327-352.
>> More details? Consult TIP2k
O2k - standard for diagnosis of mitochondrial function in health and disease - when there is little room for error.
Reference: Pesta D, Gnaiger E (2012) High-resolution respirometry. OXPHOS protocols for human cells and permeabilized fibres from small biopisies of human muscle. Methods Mol Biol 810: 25-58.
HRR since 1992: Gnaiger E, Steinlechner-Maran R, Méndez G, Eberl T, Margreiter R (1995) Control of mitochondrial and cellular respiration by oxygen. J Bioenerg Biomembr 27: 583-596.
O2k-MultiSensor: Combining HRR with fluorometry (ROS production, mt-membrane potential, ATP-production, Ca2+), potentiometric measurement of pH, TPP+ and Ca2+, amperometric measurement of NO.
• O2k-Fluorescence; • O2k-TPP and TPMP; • O2k-pH; • O2k-NO
get O2k-Connected .. it's not Warburg, it's O2k
>> O2k versus XFe - why it matters
OROBOROS - Top 10 Reasons: Leading technology, sole source, long-term experience, economical, no investors, no expensive advertising, scientific committment, Corporate Social Responsibility ...
- a new Quality in Science
O2k-Feedback: 'Once you've had a taste of high-performance, there's no going back'.
Back from Everest Base Camp and Kathmandu with 5 O2k
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Gentle Science Shapes the World
►Bioblast ►O2k-Catalogue ►O2k-Fluorescence
►MitoPedia Glossary: Respiratory states